Cell and Tissue Bioengineering
Tissue engineering and regenerative medicine are research areas in constant progress. The increasing integration between different competences and disciplines, such as biology, biochemistry, biomaterials, medicine and engineering has led to promising outcomes in the regeneration of specific tissues in vitro.
We have started several projects in this field recently, with the aim of studying culture systems for cardiac tissue engineering and aortic homograft recellularisation, rotary systems for bio-artificial liver support, perfusion systems for stem cells expansion/differentiation and fluidic chambers for neuron growth in-vitro. We are committed to the design and fabrication of bioreactors comprising perfusion systems and systems for the application of mechanical, electrical and chemical stimuli. Our general approach involves a synergistic use of computational (CAD, CFD, CSD) and experimental techniques, considering the cell-culture protocols for the specific investigated tissue and the integration of the different constituents involved (i.e. the scaffolds, the bioreactor, the stimulation, sensoring and monitoring strategies). Expertise and facilities are available to in-house design and build up devices equipped with mechanical and electromechanical stimulation, sensor monitoring and custom made control software. Our activities in this field are typically carried out in collaboration with groups of biologists and/or clinicians involved in the practical use of our culture systems.
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Research
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